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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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Year : 2009  |  Volume : 16  |  Issue : 3  |  Page : 107-111

Results from the tube versus trabeculectomy study

Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, Florida, USA

Correspondence Address:
Steven J Gedde
Bascom Palmer Eye Institute, 900 N.W. 17th Street, Miami, Florida 33136
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.56219

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The Tube Versus Trabeculectomy (TVT) Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery to trabeculectomy with mitomycin (MMC) in eyes with previous cataract and/or failed glaucoma surgery. Tube shunt surgery was more likely to maintain intraocular pressure (IOP) control and avoid persistent hypotony, reoperation for glaucoma, or loss of light perception vision than trabeculectomy with MMC during the first year of follow-up. Both surgical procedures had similar IOP reduction at 1 year, but less supplemental medical therapy was used following trabeculectomy. The incidence of postoperative complications was higher after trabeculectomy with MMC relative to tube shunt surgery, but serious complications associated with vision loss and/or reoperation developed with similar frequency after both of the procedures. There was no significant difference in the rate of vision loss following trabeculectomy with MMC and tube shunt surgery after 1 year of follow-up. Cataract progression was common, but occurred with similar frequency with both of the surgical procedures.

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