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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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Year : 2010  |  Volume : 17  |  Issue : 1  |  Page : 60-62

What is central toxic keratopathy syndrome if it is not diffuse lamellar keratitis grade IV?

1 Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, UT, USA
2 The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, UT, USA
3 University of Utah School of Medicine, Salt Lake City, UT, USA

Correspondence Address:
Yousuf M Khalifa
Moran Eye Center, 50 North Medical Drive, Salt Lake City, UT 84132
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.61218

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The Central Toxic Keratopathy (CTK) syndrome describes a rare, acute, self-limited, non-inflammatory process that yields central corneal opacification and significant hyperopic shift after refractive surgery. Despite being exceedingly rare, certain clinical features of CTK give the condition a striking resemblance to other more serious inflammatory conditions, including diffuse lamellar keratitis (DLK). As the authors demonstrate in this article, despite the overlapping clinical features, CTK is a disease process that is distinct from DLK and, therefore, in need of distinct management interventions.

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