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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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Year : 2010  |  Volume : 17  |  Issue : 2  |  Page : 175-179

Role of new magnetic resonance imaging modalities in diagnosis of orbital masses: A clinicopathologic correlation

1 Mansoura Ophthamic Center, Mansoura University, Mansoura, Egypt
2 Department of Radiology, Mansoura University, Mansoura, Egypt
3 Department of Pathology, Mansoura University, Mansoura, Egypt

Correspondence Address:
Hanem Kishk
Ophthalmology Center, Faculty of Medicine, Mansoura University, Mansoura
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.63077

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Purpose: To evaluate the role of diffusion-weighted magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (MRS) in the diagnosis of different orbital masses and their advantages over conventional MRI. Materials and Methods: The study included 20 patients presenting with proptosis. Every patient was subjected to thorough clinical examination, conventional MRI "T1 weighted, T2 weighted, and postcontrast T1 weighted if needed," diffusion-weighted MRI, and proton MRS. Orbitotomy was performed, the orbital mass was excised, and histopathological examination was performed. Results: Diffusion-weighted MRI could differentiate between benign lesions and malignant tumors in 70% of cases; however, overlap occurred in 30% of cases with benign tumors showing restricted diffusion whereas proton MRS could differentiate between benign and malignant tumors in 90% of cases. Conclusion: Diffusion-weighted MRI and proton MRS can potentially increase the accuracy of diagnosis of orbital masses through in vivo tissue characterization. Magnetic resonance spectroscopy seems to be the more accurate modality.

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