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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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SYMPOSIUM - ONCOLOGY UPDATE
Year : 2010  |  Volume : 17  |  Issue : 3  |  Page : 210-216

Exoresection and endoresection for uveal melanoma


1 Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey
2 Department of Ophthalmology, Innsbruck Medical University, Innsbruck, Austria

Correspondence Address:
Kaan Gunduz
Mesa Koza Plaza 24/18, Küpe Sok, GOP 06700, Ankara
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-9233.65494

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Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or "Exoresection" via a partial lamellar sclerouvectomy and "Endoresection" via a pars plana vitrectomy. While exoresection is more applicable to anteriorly located tumors with ciliary body and/or iris involvement, endoresection is more suitable for posteriorly located tumor without ciliary body involvement. Both approaches are suitable for large tumors with >8 mm in thickness. In general, eyes containing these large tumors have a very dismal prognosis regarding long-term visual function, eye retention, and irradiation-induced side effects. By removing the tumor burden from the eye, histopathologic and cytogenetic information of the tumor is available and complications associated with the so-called toxic tumor syndrome are avoided. However, both types of surgical resection are challenging surgical procedures, bearing the risk of early and late postoperative complications.


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