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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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CASE REPORT
Year : 2010  |  Volume : 17  |  Issue : 3  |  Page : 270-274

Idiopathic choroidal neovascularisation as the inaugural sign of multiple evanescent white dot syndrome


1 Centre for Specialized Ophthalmic Care (COS), University of Genova, Genova; Eye Clinic, Department of Neurosciences, Ophthalmology and Genetics, University of Genova, Genova, Italy
2 Centre for Specialized Ophthalmic Care (COS), University of Genova, Genova, Italy; University of Lausanne, Lausanne, Switzerland

Correspondence Address:
Carl Peter Herbort
Centre for Specialized Ophthalmic Care, Centre d'Ophtlamologie Spécialisée (COS) 6, rue de la Grotte, 1003 Lausanne, Switzerland

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-9233.65490

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We report a case of multiple evanescent white dot syndrome (MEWDS) that presented with putative idiopathic choroidal neovascularisation (ICNV) before showing angiographic signs typical of MEWDS. A 16-year-old male presented with unilateral metamorphopsias and visual loss in his left eye. ICNV with subretinal hemorrhage was diagnosed and treated with intravitreal Avastin® . Fifteen days later, regression of choriodal neovascularization (CNV) was documented together with the appearance of fluorescein angiography (FA) and indocyanine green angiography (ICGA) signs typical for MEWDS, that included faint mottled FA hyperfluorescence in the mid-peripheral fundus, irregularly shaped mid-peripheral ICGA dark areas in the intermediate angiographic phase that were clearly delineated in the late phase as well as peripapillary hypofluorescence. Fundus examination appeared completely normal during the follow-up except for the CNV hemorrhage noted at the initial visit. This case demonstrates the need to consider ICNV as a diagnosis of exclusion until inflammatory causes have been eliminated. In this case, the underlying occult inflammatory condition would have been missed without the ICGA data that clearly showed signs of MEWDS that was supported by FA findings.


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