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BOOK REVIEW
Year : 2012  |  Volume : 19  |  Issue : 1  |  Page : 169  

Ocular Angiogenesis: Principles and Practice


Editor-in-Chief, Middle East African Journal of Ophthalmology (MEAJO), PO Box 7947, Riyadh 11472, Kingdom of Saudi Arabia

Date of Web Publication20-Jan-2012

Correspondence Address:
Deepak P Edward
Editor-in-Chief, Middle East African Journal of Ophthalmology (MEAJO), PO Box 7947, Riyadh 11472
Kingdom of Saudi Arabia
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Edward DP. Ocular Angiogenesis: Principles and Practice. Middle East Afr J Ophthalmol 2012;19:169

How to cite this URL:
Edward DP. Ocular Angiogenesis: Principles and Practice. Middle East Afr J Ophthalmol [serial online] 2012 [cited 2019 Aug 19];19:169. Available from: http://www.meajo.org/text.asp?2012/19/1/169/92137


Editors: Arup Das and Thomas Friberg

Publishers: Wolters Kluwers/Lippincott Williams and Wilkins: 2010

Pages: 464

Abnormal ocular angiogenesis is a leading cause of vision loss globally. Though the disorders involving angiogenesis mainly involve the choroid and retina, other structures such as the anterior chamber angle and cornea may also be affected.

This book, which contains contributions from a global group of clinicians and basic scientists, provides a comprehensive overview of the basic and clinical aspects of treatment of abnormal angiogenesis in the eye.

The first few chapters are devoted to the pathophysiology and molecular mechanisms involved in angiogenesis and provide a practical understanding of the basis of clinical therapy that is evolving rapidly.

A section of practice describes the current antiangiogenic therapies available for treating various ocular diseases that are affected by abnormal blood vessels. These include age-related macular degeneration, diabetic macular edema, retinopathy of the prematurity and central retinal vein occlusions. Comprehensive data is provided on some of the major clinical trials involving angiogenesis in the last few years. There are also chapters that discuss the treatment of corneal neovascularization and neovascular glaucoma. It also provides information on the pharmacokinetics and safety issues involved in the treatment with anti-VEGF agents. The book provides a balanced approach to the treatment of angiogenesis in the posterior segment of the eye by providing a perspective on the role of laser and photodynamic therapy.

The last section of the book describes evolving therapies for the treatment of ocular angiogenesis and nicely discusses the challenges of drug delivery involved in the new approaches to treatment as well as financial and regulatory implications of newer anti-antigenic therapy.

The book contains high-quality photographs, tables and figures that guide the reader to understand some of the complex issues involved in ocular angiogenesis.

An important feature of this book is its availability online. The online version of the book will be continuously updated with new relevant information regarding ocular angiogenesis as it becomes available. This will provide clinicians and researchers up-to-date information in this rapidly progressive field on newer anti-angiogenic drugs and approaches to therapy.

In summary, the editors are to be commended for a book that enhances our understanding of ocular angiogenesis and the therapeutic approaches to this devastating group of disorders. The book is not only appropriate for researchers in the field of ocular angiogenesis, but also a wider scientific audience and clinicians will benefit from the contents of this book.




 

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