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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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CASE REPORT
Year : 2012  |  Volume : 19  |  Issue : 2  |  Page : 265-268

Combination of intracameral and intrastromal voriconazole in the treatment of recalcitrant Acremonium fungal keratitis


Department of Ophthalmology, American University of Beirut, Beirut, Lebanon

Correspondence Address:
Randa S Haddad
American University of Beirut - Medical Center, P.O. Box 11-0236/D27, Beirut
Lebanon
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-9233.95271

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We present a report of a 28-year-old female with fungal keratitis due to Acremonium that was unresponsive to full medical therapy over 3 weeks. The patient was treated with superficial keratectomy, intrastromal and intracameral voriconazole injections. There was a marked clinical improvement beginning on day 3 post-therapy that was sustained until the last follow-up at 6 months. This is the first case of fungal keratitis due to Acremonium treated by a combination of intrastromal and intracameral voriconazole. This cost-effective treatment modality proved to be significant in impeding the progression of this potentially blinding disease and improving visual prognosis.


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