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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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Year : 2012  |  Volume : 19  |  Issue : 4  |  Page : 392-396

The effect of software upgrade on optical coherence tomography measurement of the retinal nerve fiber layer thickness

Department of Ophthalmology, Rocky Mountain Lions Eye Institute, University of Colorado at Denver, Aurora, CO, USA

Correspondence Address:
Leonard K Seibold
Department of Ophthalmology, Rocky Mountain Lions Eye Institute, 1675 North Aurora Court, Mail Stop F-731, Aurora, CO
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.102745

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Purpose: To determine the effect of software upgrades on retinal nerve fiber layer (RNFL) thickness measurements taken by spectral domain optical coherence tomography (SD-OCT). Methods: Eighty normal eyes (40 patients) were scanned for RNFL thickness measurements using Spectralis (Heidelberg Engineering, Heidelberg, Germany) SD-OCT. Scan analysis was performed using version 4.0 software and then reanalyzed with version 5.1.3. Student paired t testing and Pearson's correlation coefficient were used for statistical analysis. Results: Average and quadrant RNFL thicknesses generated using version 4.0 and 5.1.3 software on Spectralis demonstrated high correlation (r = 0.955-0.998). Average RNFL thickness using version 4.0 was 0.08΅m thinner than version 5.1.3 (p = 0.409). Quadrant RNFL differences ranged from -0.26 to +0.97΅m (p = 0.146-0.915). Segmentation errors were reduced 33% after the upgrade. Conclusion: Minor RNFL thickness changes may occur after software upgrades in Spectralis OCT. The differences did not reach statistical significance but segmentation errors were improved.

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