About MEAJO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions to authors | Online submission | Subscribe | Advertise | Contact | Login 
Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
Users Online: 2479   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Year : 2012  |  Volume : 19  |  Issue : 4  |  Page : 432-435

Long-term management of orbital and systemic reactive lymphoid hyperplasia with rituximab

1 Department of Ophthalmology, University of California-San Francisco, San Francisco, California, USA
2 Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA; King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia
3 Massachusetts Eye and Ear Infirmary, Harvard University School of Medicine, Boston, Massachusetts, USA

Correspondence Address:
Timothy J McCulley
The Wilmer Eye Institute, Johns Hopkins School of Medicine, 600 North Wolfe Street, Wilmer 110, Baltimore, MD, USA

Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.102770

Rights and Permissions

Rituximab, a monoclonal antibody to the B cell marker CD20, is becoming increasingly popular in the treatment of various orbital disorders. In this university-based interventional case series, we describe two patients with bilateral orbital and extra-orbital reactive lymphoid hyperplasia (RLH) treated with rituximab. Initially both had favorable responses; but roughly a year later recurrent disease necessitated maintenance therapy in both cases. Both again responded to additional courses of rituximab. Although recalcitrant disease may persist after treatment, rituxmab may play a role in the management of RLH with widespread involvement.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded112    
    Comments [Add]    

Recommend this journal