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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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SYMPOSIUM - OCULAR THERAPEUTICS OF THE FUTURE
Year : 2013  |  Volume : 20  |  Issue : 1  |  Page : 38-45

Future perspectives for regenerative medicine in ophthalmology


1 Translational Tissue Engineering Center, Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Mary Land, USA
2 Ophthalmology and Visual Sciences Research Chair, School of Medicine and Health Sciences, Tecnológico de Monterrey, Monterrey, Mexico

Correspondence Address:
Jennifer Elisseeff
5031 Smith Building, 400 N. Broadway, Baltimore, MD 21231
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0974-9233.106385

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Repair and reconstruction of the cornea has historically relied on synthetic materials or tissue transplantation. However, the future holds promise for treatments using smart biomaterials and stem cells that direct tissue repair and regeneration to ultimately create new ocular structures that are indistinguishable from the original native tissue. The cornea is a remarkable engineering structure. By understanding the physical structure of the tissue and the resulting impact of the structure on biological function, we can design novel materials for a number of ophthalmic clinical applications. Furthermore, by extending this structure-function approach to characterizing corneal disease processes, new therapies can be engineered.


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