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Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
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CASE REPORT
Year : 2013  |  Volume : 20  |  Issue : 1  |  Page : 83-86

Transient increased exudation after photodynamic therapy of intraocular tumors


Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, PA, USA

Correspondence Address:
Arman Mashayekhi
Ocular Oncology Service, Suite 1440, Wills Eye Institute, 840 Walnut Street, Philadelphia, PA 19107
USA
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Source of Support: Support provided by a donation from Michael, Bruce, and Ellen Ratner, New York, NY 20 (JAS, CLS), the Paul Kayser International Award of Merit in Retina Research, Houston TX (JAS), Mellon Charitable Giving from the Martha W. Rogers Charitable Trust, Philadelphia, PA (CLS) and the Eye Tumor Research Foundation, Philadelphia, PA (CLS, JAS), Conflict of Interest: None


DOI: 10.4103/0974-9233.106400

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To report transient increased exudation after photodynamic therapy (PDT) of three different intraocular tumors (retinal hemangioblastoma, retinal astrocytoma, amelanotic choroidal melanoma). PDT with verteporfin (6 mg/m [2] body surface area) was delivered at a dose of 50 J/cm [2] and intensity of 600 mW/cm [2] over 83 s. All patients experienced decreased vision within a few days following PDT. Optical coherence tomography showed development of subfoveal fluid in all cases and noncystoid intraretinal edema in the eye with juxtapapillary retinal hemangioblastoma. There was complete absorption of retinal/subretinal fluid with improvement of visual acuity to 20/20 in all cases between 3 weeks to 4 months after PDT.


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