About MEAJO | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions to authors | Online submission | Subscribe | Advertise | Contact | Login 
Middle East African Journal of Ophthalmology Middle East African Journal of Ophthalmology
Users Online: 585   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
Year : 2013  |  Volume : 20  |  Issue : 4  |  Page : 353-356

Bilateral proliferative retinopathy as the initial presentation of chronic myeloid leukemia

Department of Ophthalmology, Hospital de Santo António-Centro Hospitalar do Porto, Portugal

Correspondence Address:
Mafalda S. F. Macedo
Hospital de Santo António-Centro Hospitalar do Porto, Serviço de Oftalmologia, Largo Prof. Abel Salazar, 4099-001 Porto
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0974-9233.120016

Rights and Permissions

The authors report a rare case of a 48-year-old male with chronic myeloid leukemia (CML) who initially presented with a bilateral proliferative retinopathy. The patient complained of recent visual loss and floaters in both eyes (BE). Ophthalmologic evaluation revealed a best corrected visual acuity (BCVA) of 20/50 in the right eye and 20/200 in the left eye (LE). Fundoscopy showed the presence of bilateral peripheral capillary dropout with multiple retinal sea fan neovascularisations, which were confirmed on fluorescein angiography. Full blood count revealed hyperleukocytosis, thrombocytosis, anemia, and hyperuricemia. Bone marrow aspiration and biopsy showed the reciprocal chromosomal translocation t (9;22), diagnostic of CML. The patient was started on hydroxyurea, allopurinol and imatinib mesylate. He received bilateral panretinal laser photocoagulation and a vitrectomy was performed in the LE. The patient has been in complete hematologic, cytogenetic, and major molecular remission while on imatinib and his BCVA is 20/25 in BE.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded217    
    Comments [Add]    
    Cited by others 7    

Recommend this journal