One year outcomes of photorefractive keratectomy with the application of mitomycin-C in the treatment of mild to moderate hyperopia
Alireza Habibollahi1, Hassan Hashemi1, Mohammad Amin Seyedian1, Shiva Mehravaran1, Soheila Asgari2, Sam Habibollahi3, Sina Habibollahi4, Mehdi Khabazkhoob5
1 Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran
2 Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, International Campus, Tehran, Iran
3 Department of Ophthalmology, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Medicine, Faculty of Medicine, Islamic Azad University Tehran medical Sciences, Tehran, Iran
5 Department of Epidemiology, Faculty of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Noor Eye Hospital, #96 Esfandiar Blvd., Valilasr Avenue, Tehran 19686
Source of Support: None, Conflict of Interest: None
Purpose: To evaluate refractive and visual outcomes of photorefractive keratectomy with mitomycin.C. (PRK.MMC) for the treatment of mild to moderate hyperopia.
Materials and Methods: This case series enrolled 21 patients with up to +5.50 diopters (D) of hyperopia. All 42 eyes were treated with the Concerto (Wavelight) or the Technolas 217-Z (Bausch and Lomb) excimer laser. Outcome measures included best corrected distance vision acuity (BCVA) and uncorrected distance vision correction and refraction at 1, 3, 6, and 12 months postoperatively.
Results: Mean patient age was 44.8 ± 11.3 years. Preoperatively, mean manifest refractive spherical equivalent (MRSE) was + 2.00 D ± 0.76 D and mean spherical refractive error was + 2.57 D ± 0.87 D (range, +1.25 D to + 5.50 D). At 12 months postoperatively, mean MRSE was + 0.1 D ± 0.61 D. MRSE was within ± 0.50 D of emmetropia in 29 eyes (69%), and 18 eyes (43%) had 20/20 uncorrected distant visual acuity. BCVA increased by two lines or more in three eyes (7.1%) and one line in two eyes (4.7%); 31 eyes showed no change, three eyes (7.1%) lost one line, and three other eyes (7.1%) lost two lines of BCVA. No eyes lost more than two lines of BCVA. Complications included Grade 2 peripheral haze in two eyes which cleared by 12 months postoperatively.
Conclusion: PRK-MMC was a safe and predictable method for the correction of mild to moderate hyperopia.