Year : 2009 | Volume
: 16 | Issue : 3 | Page : 146--150
Vascular risk factors for open angle glaucoma in African eyes
Afekhide E Omoti1, Malachi E Enock2, Valentina W Okeigbemen1, Benedicta A Akpe1, Ukamaka C Fuh2
1 Department of Ophthalmology, University of Benin Teaching Hospital, P.M.B 1111, Benin City, Nigeria
2 Department of Ophthalmology, Irrua Specialist Teaching Hospital, P.M.B. 08, Irrua, Edo State, Nigeria
Context : The exact patho physiological mechanizm of optic nerve damage in glaucoma is not fully understood.
Aim : To assess the vascular risk factors in open angle glaucoma in African eyes.
Settings and Design : Prospective multicenter hospital-based study in Edo State, Nigeria.
Materials and Methods : Three hundred and twenty-two glaucoma patients and 184 control subjects were included in the study comprising 200 male glaucoma patients (62.11%) and 122 females (37.89%). A cohort of consecutive patients with a diagnosis of primary open angle glaucoma and age and sex matched control subjects were included in this prospective, cross-sectional, and multicenter hospital-based study conducted during the period January-June 2008. Blood pressure (BP), pulse and intraocular pressure findings were recorded and mean BP, pulse and perfusion pressure for each eye calculated.
Statistical Analysis Used : Mean, standard deviations, 95% confidence intervals, Welch«SQ»s t test, and Fisher«SQ»s exact test were calculated.
Results : The mean IOP in the 644 eyes of the 322 glaucoma patients was 22.65 mmHg (SD plus/minus 11.06). The systolic blood pressure (P < 0.0001), diastolic blood pressure (P < 0.0001), mean arterial blood pressure
(P < 0.0001), pulse pressure (P < 0.01), systolic perfusion pressure (P < 0.01) were all significantly higher in glaucoma patients than in control.
Conclusions : Higher systolic, diastolic, mean arterial BP and pulse pressure was found in Black African patients with open angle glaucoma.
Afekhide E Omoti
Department of Ophthalmology, University of Benin Teaching Hospital, P.M.B 1111, Benin City, Edo State
|How to cite this article:|
Omoti AE, Enock ME, Okeigbemen VW, Akpe BA, Fuh UC. Vascular risk factors for open angle glaucoma in African eyes.Middle East Afr J Ophthalmol 2009;16:146-150
|How to cite this URL:|
Omoti AE, Enock ME, Okeigbemen VW, Akpe BA, Fuh UC. Vascular risk factors for open angle glaucoma in African eyes. Middle East Afr J Ophthalmol [serial online] 2009 [cited 2020 Apr 1 ];16:146-150
Available from: http://www.meajo.org/article.asp?issn=0974-9233;year=2009;volume=16;issue=3;spage=146;epage=150;aulast=Omoti;type=0