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  Indian J Med Microbiol
 

Figure 1: A schematic representation of some nanoparticle platforms used as ocular drug delivery systems. (a) Liposomes (~100-400nm) are small spherical artificial vesicles typically made with lipid bilayers, (b) Nanoparticles (~20-200 nm) are typically made with biodegradable polymers for sustained drug release, (c) Nanocapsules (~10-1000 nm) can encapsulate relatively large amounts of drugs and nucleic acids such as DNA, microRNA, siRNA and shRNA, (d) Micelles (~10-100 nm) are self-assembled amphiphilic particles that can encapsulate both lipophilic or lipophobic drugs stabilized by surfactants, (e) Dendrimers (~3-20 nm) are monodisperse macromolecules that can be used to encapsulate or covalently conjugate drugs, targeting moieties & imaging agents, (f) Nanoconjugates are polymers to which drug molecules are covalently conjugated

Figure 1: A schematic representation of some nanoparticle platforms used as ocular drug delivery systems. <b>(a) Liposomes (~100-400nm)</b> are small spherical artificial vesicles typically made with lipid bilayers, <b>(b) Nanoparticles (~20-200 nm)</b> are typically made with biodegradable polymers for sustained drug release, <b>(c) Nanocapsules (~10-1000 nm)</b> can encapsulate relatively large amounts of drugs and nucleic acids such as DNA, microRNA, siRNA and shRNA, <b>(d) Micelles (~10-100 nm)</b> are self-assembled amphiphilic particles that can encapsulate both lipophilic or lipophobic drugs stabilized by surfactants, <b>(e) Dendrimers (~3-20 nm)</b> are monodisperse macromolecules that can be used to encapsulate or covalently conjugate drugs, targeting moieties & imaging agents, <b>(f) Nanoconjugates</b> are polymers to which drug molecules are covalently conjugated