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  Indian J Med Microbiol
 

Figure 1: Clinical and cytopathological features of iris melanoma in a child. (a) An 8-year-old child with a vascular amelanotic iris mass. (b) Ultrasound biomicroscopy showing iris thickening (arrow), but no ciliary body involvement. Fluorescein angiogram showing (c) early features of normal iris vascularity and nasal tumor enhancement with (d) late intense hyperfluorescence. (e) Cytopathology of fine-needle aspiration biopsy specimen demonstrating a cluster of atypical spindle cells with ovoid nuclei, slightly coarse chromatin, and prominent central nucleoli (Papanicolaou stain, ×250). (f) Tumor cells in fine-needle aspiration biopsy are immunoreactive for HMB45 (IHC for HMB45; ×250)

Figure 1: Clinical and cytopathological features of iris melanoma in a child. (a) An 8-year-old child with a vascular amelanotic iris mass. (b) Ultrasound biomicroscopy showing iris thickening (arrow), but no ciliary body involvement. Fluorescein angiogram showing (c) early features of normal iris vascularity and nasal tumor enhancement with (d) late intense hyperfluorescence. (e) Cytopathology of fine-needle aspiration biopsy specimen demonstrating a cluster of atypical spindle cells with ovoid nuclei, slightly coarse chromatin, and prominent central nucleoli (Papanicolaou stain, ×250). (f) Tumor cells in fine-needle aspiration biopsy are immunoreactive for HMB45 (IHC for HMB45; ×250)